Male Health 2025: Innovation in treatment

Male Health 2025: Innovation in treatment

I. Cardiovascular diseases: new borders of cardiology for men

IA genetic predisposition and preventive genetics

• Understanding the genome: 2025 marks the era of the decoding of genetic markers associated with an increased risk of cardiovascular diseases (SVD) in men. This includes the identification of specific SNP (single -okleotide polymorphisms) associated with hypertension, hypercholesterolemia and cardiomyopathy.
• Personalized genetic assessment: Genetic panels are becoming available that offer men an assessment of their individual risk of developing SVD based on DNA analysis. These panels take into account genetic options associated with lipid metabolism, inflammation and endothelium function.
• Preventive strategies based on genetics: Knowing their genetic risk, men can take proactive measures to reduce this risk. This includes a modification of lifestyle, such as adjusting the diet and physical activity, as well as the early beginning of drug therapy, if necessary.
• CRISPR and gene therapy (experimental): Although still in the experimental phase, CRISPR-CAS9 genetic therapy promises editing genes associated with the SVD, potentially forever reducing the risk of predisposed individuals. Clinical trials study the use of CRISPR to modify genes that regulate cholesterol metabolism and the function of the heart muscle.

IB non -invasive methods of heart visualization

• Advanced CT angiography: Computer tomographic angiography (KTA) has become more accurate and less invasive, allowing the coronary arteries with a lower dose of irradiation. The new algorithms of artificial intelligence (AI) improve the interpretation of KTA images, revealing even small plaques and narrowing.
• Magnetic resonance imaging (MRI) of the heart with high resolution: MRI of the heart provides detailed visualization of the structure and function of the heart without the use of ionizing radiation. New MRI sequences allow you to more accurately evaluate myocardial perfusion (blood supply), vitality and scarring, which helps in the diagnosis and treatment of coronary heart disease.
• Ultrasound examination of the heart with contrast: Contrast substances based on micropouses improve the visualization of heart and blood flow chambers during ultrasound examinations. This allows you to more accurately evaluate the function of the left ventricle, identify blood clots and evaluate myocardial perfusion.
• Wearable cardiological devices: The integration of wearable technologies, such as smart watches and breast belts, provides continuous monitoring of ECG and other parameters of cardiac activity. These data can be used for early detection of arrhythmias, assessing the risk of heart failure and monitoring the effectiveness of treatment.

IC Targeted pharmacotherapy of cardiovascular diseases

• PCSK9-Ingitors: PCSK9 inhibitors remain an important class of drugs to reduce LDL cholesterol (low density lipoproteins). New studies are studying the advantages of these drugs in men with the established SVD and a very high risk.
• New anticoagulants (PLA): The PLA (direct oral anticoagulants) became a preferred option for the prevention and treatment of thromboembolic events, such as stroke and deep vein thrombosis. New generations of the PLA with improved safety profiles and a lower risk of bleeding are under development.
• Preparations affecting inflammation: Inflammation plays an important role in the development and progression of the SSZ. Medicines aimed at inflammatory paths, such as colchicin and monoclonal antibodies aimed at IL-1β (Interleukin-1 beta), show promising results in reducing the risk of heart events.
• Preparations for the treatment of heart failure with the preserved emission fraction (SNSFV): SNSFV is a common form of heart failure, which had previously been poorly treated. New drugs, such as SGLT2 inhibitors (sodium-glucose coter inhibitors 2) have proved their effectiveness in improving symptoms and reducing the risk of hospitalization in patients with SNSFV.

ID invasive procedures and robotic surgery

• Transcate implantation of the aortic valve (TAVI): Tavi has become a widespread alternative to the surgical replacement of the aortic valve in patients with aortic stenosis. New generations of TAVI valves with improved durability and lower risk of complications are available for a wider circle of patients.
• Coronal coronary angioplasty (ChKA) using biodiversity stents: Bisstalling stents, which over time dissolve in the body, reduce the risk of long -term complications associated with traditional metal stents. Advanced biodiversity stents with improved strength and reduced risk of thrombosis are under development.
• Robotized coronary angioplasty: Robotized systems allow surgeons to perform ChKA with greater accuracy and control, potentially reducing the risk of complications and improving the results.
• Municipal Surgery of the Heart: Miniyinvasive heart surgery, performed through small cuts, is becoming more and more popular. This approach leads to a smaller amount of pain, a shorter stay in the hospital and faster recovery compared to traditional open surgery of the heart.

II. Urological diseases: from early diagnosis to innovative treatment methods

II.A. Prostate cancer: early detection and personalized therapy

• PSA and innovative biomarkers: Although the level of prostat-specific antigen (PSA) remains an important tool for screening, new biomarkers, such as PCA3, the prostate health index (Phi) and 4KScore, provide a more accurate assessment of the risk of prostate cancer and help to avoid unnecessary biopsies.
• Multi -parametric MRI prostate (MPMT): MPMRT has become an important tool for identifying and characterizing the lesions of the prostate gland. AI technologies improve the interpretation of MPMRT images, helping in the detection of clinically significant prostate cancer.
• The aiming biopsy of the prostate gland: The aiming biopsy, performed using the merger of images of MRI and ultrasound or robotic systems, allows you to more accurately take samples from suspicious areas detected on MPMRI, increasing the accuracy of diagnosis and reducing the risk of cancer underestimation.
• Active observation and personalized therapy: For men with a low risk of prostate cancer, active observation, including regular monitoring of the level of dog, examination and biopsy, is becoming an increasingly common alternative to immediate treatment. Delivery decisions are made on the basis of the individual characteristics of the patient and the progression of the disease.
• Target therapy: Targeted therapy aimed at specific molecular characteristics of the prostate cancer cells is becoming more important. This includes PARP inhibitors (Paul (ADF Ribose)-polymerase) for men with mutations in DNA reparation genes, as well as immunotherapy for men with metastatic castration-resisting prostate cancer (microdistrict).
• Radioligand therapy: Radioligand therapy using radioactive molecules that are aimed at specific proteins on the surface of the prostate cancer cells, shows promising results in the treatment of MKRRPG. LU-177 PSMA is one of the examples of a radio league that is aimed at an antigen Prostat-specific membrane (PSMA), which is expressed in large numbers on prostate cancer cells.
• Focused ultrasound of high intensity (HIFU): HIFU is a non -invasive procedure that uses focused ultrasonic waves to heat and destroy the prostate cancer cells. HIFU may be a treatment option for men with localized prostate cancer.
• Cryoablation: Crybulation uses an extreme cold to freeze and destroy the prostate cancer cells. Like HIFU, cryoBlaces may be a treatment option for men with localized prostate cancer.

II.B. Prostate benign hyperplasia (DGPZ): minimally invasive treatment methods

• Drug therapy: Inhibitors of alpha-adrenergic receptors and inhibitors of 5-alpha reductase remain the main drugs for the treatment of symptoms of DGPZH. New drugs and combinations of drugs with improved effectiveness and safety profiles are in development.
• Transurethral prostate resection (Turp): The turp remains the gold standard of the surgical treatment of DHCH. However, new, less invasive procedures are becoming more and more popular.
• Transurethral microwave thermotherapy (TUMT): Tumt uses microwave radiation to heat and destroy the tissue of the prostate gland, facilitating the symptoms of DHCH.
• Transuretral Ivatol Ablation (TUNA): Tuna uses radio frequency energy to heat and destroy the tissue of the prostate gland.
• Prostatic urethral lifting (PUL): PUL is a minimum invasive procedure that includes the placement of implants for pulling the tissue of the prostate from the urethra, relief of the symptoms of DHC without cutting or removing the tissue.
• Prostate water ablation (Rezūm): Rezūm uses pair injections to abuse the tissue of the prostate gland.
• Embolization of the arteries of the prostate gland (EAP): EAP is a minimum invasive procedure in which small particles are introduced into arteries that feed the prostate gland, blocking the bloodstream and causing a contraction of the gland.

II.C. Erectile dysfunction (ED): New Horizons of Treatment

• FDE-5 inhibitors: Phosfodesterase-5 (FDE-5) inhibitors, such as sildenafil, tadalafil and vardenafil, remain the cornerstone of drug treatment of Ed. New FDE-5 drugs with improved efficiency, safety profile and action are in development.
• Intracavernous injections: Alprostadil injections in the penis remain an effective treatment option for men who do not respond to oral drugs.
• Vacuum devices: Vacuum devices can help create an erection by drawing blood into the penis.
• Surgical treatment (penis prostheses): Personal dentures can be a treatment option for men with a severe ED, which is not amenable to other methods of treatment.
• Low intensity (low intensity): low-intensity): UVT low intensity is a non -invasive procedure that uses sound waves to stimulate the growth of new blood vessels in the penis, improving blood flow and erectile function.
• Gene therapy (experimental): Gene therapy, aimed at improving blood flow and endothelium function in the penis, is in development as a potential option for the treatment of ED.

II.D. Male infertility: Improving the possibilities for paternity

• Extended sperm analysis: In addition to the traditional analysis of sperm, new tests can evaluate fragmentation of sperm DNA, morphology and mobility with greater accuracy.
• Microsurgical varicocelicectomy: Microsurgical varicocelicectomy is a surgical procedure to restore varicocele (enlarged veins in the scrotum), which can improve sperm quality.
• Removing sperm from testicles (TSE) and microsurgical extraction of sperm from the testicles (Microtese): TESE and Microtese are surgical procedures for extracting sperm directly from the testicles for use for extorporeproof fertilization (ECO). Microtese uses a microscope to identify the areas of testicles with a greater probability of sperm, increasing the success of sperm extraction.
• Artificial fertilization (IO) and IVF: IO and IVF are methods of auxiliary reproduction that can help pairs to conceive a child.
• Genes editing (experimental): Genes editing using CRISPR-CAS9 may have a potential for correcting genetic defects that cause male infertility, but this area is still in the early stages of development.

III. Mental health: elimination of gender differences in treatment

III.A. Depression and anxiety disorders: New strategies for men

• Recognition of gender differences: The recognition that men often experience depression and anxiety in different ways than women is crucial. Men can be less inclined to express sadness or emotional pain and can instead show irritability, anger or reckless behavior.
• Specialized treatment methods: Therapeutic approaches adapted to the needs of men can be more effective. This may include emphasis on solving problems, developing skills in overcoming difficulties and increasing emotional awareness.
• Medication: Selective inhibitors of the reverse capture of serotonin (SIOS) and other antidepressants remain the main drugs for the treatment of depression and anxiety. However, new drugs with other mechanisms of action are in development.
• Conscious therapy: Conscious therapy (MBCT) can help men develop a greater awareness of their thoughts and feelings, reducing stress and improving emotional well -being.
• Mental health technologies: Mobile applications and online platforms provide men with convenient and affordable resources for managing their mental health.
• Virtual reality (VR): VR therapy shows promising results in the treatment of alarming disorders, such as social anxiety and post-traumatic stress disorder (PTSR).

III.B. Abuse of psychoactive substances and dependence: effective strategies for overcoming

• Cognitive-behavioral therapy (KPT): KPT is a proven method of treating disorders associated with abuse of psychoactive substances. KPT helps men to identify and change negative thoughts and behavior that contribute to abuse of psychoactive substances.
• Motivation interview (mi): Mi is a customer -oriented approach that helps men study and resolve their ambivalent feelings for a change in their behavior.
• Pharmacotherapy: Medicines can be used to reduce traction, control symptoms of cancellation and prevent relapse.
• Support groups: Support groups, such as “anonymous alcoholics” and “anonymous drug addicts”, provide men with a supporting environment for the exchange of experience and developing the skills of overcoming difficulties.
• Neurostimulation: Transcranial magnetic stimulation (TMS) and other neurostimulation methods are studied as potential methods for treating dependence.

III.C. Stress management and stability: development of survival skills

• Relaxation techniques: Relaxation techniques, such as deep breathing, progressive muscle relaxation and meditation, can help men reduce stress and improve overall well -being.
• Exercise: Regular physical exercises are a powerful way to reduce stress, improve mood and improve physical health.
• Social support: Maintaining strong social ties and participation in significant activities can help men cope with stress and increase stability.
• Development of awareness: The practice of awareness can help men develop a greater awareness of their thoughts and feelings, reducing reactivity and improving the regulation of emotions.
• Cognitive restructuring: Cognitive restructuring includes the identification and change in negative models of thinking that contribute to stress and anxiety.

IV. Endocrine disorders: hormonal balance and male health

IV.A. Testosterone deficiency (hypogonadism): new treatment strategies

• Diagnostics and evaluation: Careful diagnosis and evaluation are necessary to determine the cause of testosterone deficiency and exclude other diseases.
• Testosterone therapy (TT): TT remains the main method of treating testosterone deficiency. Various forms of TT, including injections, transdermal plasters, gels and oral drugs are available.
• Dosage optimization and monitoring: The optimal dosage of TT varies from person to person and requires careful monitoring of testosterone levels and side effects.
• Selective estrogen receptor modulators (SMER): SMER, such as Clomiphen Citrate and Tamoxifen, can stimulate testosterone production in testicles and are used as an alternative to TT in some men.
• Gonadotropin Therapy: Gonadotropin therapy using human chorionic gonadotropin (hCG) or recombinant luteinizing hormone (LH) can stimulate the production of testosterone in testicles and be used in men who want to maintain their fertility.
• New delivery methods: New TT delivery methods are developed, such as nasal sprays and implantable granules to provide more convenient and physiological methods of introducing testosterone.

IV.B. Diabetes: Management and prevention for men

• Life: Modification of lifestyle, including healthy nutrition, regular physical exercises and maintaining healthy weight, is crucial for the prevention and treatment of diabetes.
• Medication: Metformin, SGLT2 inhibitors, GLP-1 agonists and insulin are the main drugs for the treatment of diabetes. New drugs with improved efficiency and safety profile are in development.
• Continuous glucose monitoring (NMG): NMG allows men to continuously monitor the glucose level, providing data in real time, which can help them make more reasonable decisions about their treatment.
• Insulin pumps: Insulin pumps deliver insulin continuously during the day, providing more accurate control of glucose levels.
• Artificial pancreas: The artificial pancreas, which automatically regulates the delivery of insulin based on the readings of the NMG, is under development and can revolutionize diabetes.

IV.C. Thyroid diseases: diagnosis and treatment

• Diagnosis: Thyroid function tests, such as the level of TSH (thyrotropic hormone), T4 (thyroxine) and T3 (triiodothyronine), are used to diagnose thyroid diseases.
• Treatment of hypothyroidism: Levothyroxine, the synthetic form of T4, is a standard treatment for hypothyroidism.
• Treatment of hyperthyroidism: Antitiraoid drugs, radioactive iodine and surgical intervention are options for treating hyperthyroidism.

V. Infectious diseases: new approaches to prevention and treatment

VA sexually transmitted infections (IPP): screening and prevention

• Extended screening: Regular screening for IPP, such as chlamydia, gonorrhea, syphilis and HIV, is necessary for early detection and treatment.
• Vaccination: Vaccines are available for the prevention of some STIs, such as human papillomavirus (HPV) and hepatitis V.
• Antibiotic resistance: The growing problem of antibiotic resistance requires new approaches to the treatment of IPP.
• Prevention before contact (PREP): Prep is an HIV prevention strategy that includes taking antiretroviral drugs by people with a high risk of HIV infection.

VB HIV/AIDS: achievements in treatment and prevention

• Antirerovirus therapy (art): Art significantly improved life expectancy and quality of life living with HIV.
• PrEP: Prep is a highly effective HIV prevention strategy.
• Long -acting injection drugs: Long -acting injection drugs for art are in development and can provide a more convenient way to treat HIV.
• Treatment and prevention: The goal is to achieve “treatment and prevention” when HIV is eradicated or controlled in such a way that there will no longer be a risk to health or transmission.

VC Flu and Pneummonia: Vaccination and prevention

• Influenzation against influenza: An annual flu vaccination is recommended for all men, especially for those who are at high risk of complications.
• Vaccination against pneumococcal infection: Vaccination against pneumococcal infection is recommended for elderly people and people with certain diseases.
• Antivirus drugs: Antivirus drugs can be used to treat influenza and reduce the severity and duration of the disease.
• Antibiotics: Antibiotics are used to treat bacterial pneumonia.

VI. Diseases of the musculoskeletal system: preservation of mobility and functionality

VI.A. Osteoporosis: Screening and prevention of fractures

• Dencitometry: Densitometry, or Dexa scanning, is used to measure bone density and diagnosis of osteoporosis.
• Modification of lifestyle: Modification of the lifestyle, including adequate consumption of calcium and vitamin D, regular physical exercises and rejection of smoking, is crucial for the prevention of osteoporosis.
• Medication: Bisphosphonates, denosumab and teripipidide are drugs that can be used to treat osteoporosis and reduce the risk of fractures.

Vi.b. Osteoarthritis: pain control and improvement of joint function

• Pain Management: Anesthetizing, such as acetaminophen and non -steroidal anti -inflammatory drugs (NSAIDs), can be used to relieve pain in osteoarthritis.
• Physiotherapy: Physiotherapy can help improve the strength, flexibility and range of joint movements.
• Injections: Injections of corticosteroids or hyaluronic acid in the joint can provide temporary relief of pain.
• Surgical intervention: Surgical intervention, such as replacing the joint, may be necessary for men with severe osteoarthritis.

VI.C. Back pain: diagnosis and treatment

• Diagnosis: A thorough history and physical examination are necessary to determine the cause of back pain. In some cases, visualization may be required, such as x -ray, MRI or CT.
• Pain Management: Anesthetic, physiotherapy and manual therapy can be used to relieve back pain.
• Surgical intervention: Surgical intervention may be necessary for men with severe back pain, which does not respond to other methods of treatment.

VII. Dermatological diseases: skin care and skin prevention

VII.A. Skin cancer: early detection and prevention

• Self -examination of the skin: Regular self -examination of the skin is crucial for the early detection of skin cancer.
• Dermatological examinations: Regular dermatological examinations are recommended, especially for men with a high risk of skin cancer.
• Sunsmate: Sun protection, including the use of sunscreen, wearing protective clothing and avoiding peak sundials, is crucial for the prevention of skin cancer.
• Treatment: Treatment of skin cancer varies depending on the type and stage of cancer and may include surgical intervention, radiation therapy, chemotherapy and targeted therapy.

VII.B. Acne: Management and Treatment

• Local funds: Local remedies, such as benzoilproxide, salicylic acid and retinoids, can be used to treat acne.
• Octus drugs: Periral drugs, such as antibiotics and isolatinoid, can be necessary for men with severe acne.
• Laser and light therapy: Laser and light therapy can be used to treat acne and scars from acne.

VII.C. Bold: Treatment options

• Minoxidil: Minoxidil is a local drug that can help stimulate hair growth.
• Finasters: Finasteride is an oral drug that can help slow down hair loss.
• Hair transplant: Hair transplant is a surgical procedure in which hair follicles are transplanted from one area of ​​the head to another.

VIII. Gastroenterological diseases: the health of the digestive system

VIII.A. Colorectal cancer: screening and prevention

• Colonoscopy: Colonoscopy is a screening test that can be used to identify and remove polyps in the colon, which can prevent colorectal cancer.
• Other screening tests: Other screening tests for colorectal cancer include a fecal analysis for hidden blood (FIT), a COLUARD DNA analysis and virtual colonoscopy (CT-kolonography).
• Modification of lifestyle: Modification of lifestyle, including healthy nutrition, regular physical exercises and rejection of smoking, is crucial for the prevention of colorectal cancer.

VIII.B. Inflammatory diseases of the intestine (BCC): Treatment and Management

• Medication: Medicines, such as aminosalicylates, corticosteroids, immunomodulators and biological drugs, can be used for the treatment of BCC, such as Crohn’s disease and ulcerative colitis.
• Surgical intervention: Surgical intervention may be necessary for men with severe OKK.

VIII.C. Gastroesophageal reflux disease (GERB): Symptoms Management

• Modification of lifestyle: Modification of lifestyle, including rejection of smoking, avoiding certain products and drinks, and raising the head of the bed, can help relieve symptoms of GERB.
• Medication: Antacids, H2 receptor blockers and proton pump inhibitors (IPP) can be used to treat GERB.
• Surgical intervention: Surgical intervention may be necessary for men with severe GERB, which does not respond to other treatment methods.

IX. Neurological diseases: brain health and nervous system

IX.A. Alzheimer’s disease: Early detection and treatment

• Early detection: The early detection of Alzheimer’s disease is crucial for the start of treatment as early as possible.
• Cognitive tests: Cognitive tests can be used to assess the memory function and other cognitive abilities.
• Brain visualization: Brain visualization, such as MRI and PET, can help identify changes in the brain associated with Alzheimer’s disease.
• Medication: Medicines, such as cholinsterase and memantine inhibitors, can help improve cognitive functions in men with Alzheimer’s disease.
• New methods of treatment: New methods for the treatment of Alzheimer’s disease are in development, such as an adukanumab that is aimed at amyloid plaques in the brain.

IX.B. Parkinson’s disease: Symptoms Management

• Medication: Medicines, such as levodopa, dopamine agonists and MAO-B inhibitors, can be used to control the symptoms of Parkinson’s disease.
• Deep brain stimulation (fuel and lubricants): Fuel and lubricants are a surgical procedure that can help alleviate the symptoms of Parkinson’s disease.
• Physiotherapy: Physiotherapy can help improve balance, coordination and mobility in men with Parkinson’s disease.

IX.C. Stroke: prevention and treatment

• Prevention: Stroke prevention includes risk factors, such as high blood pressure, high cholesterol and smoking.
• Treatment: Treatment of a stroke includes thrombolysis (drug dissolution of a thrombus) and mechanical removal of a thrombus (thrombectomy).
• Rehabilitation: Rehabilitation is crucial for the restoration of function after a stroke.

X. Oncological diseases: new directions of the fight against cancer

XA lung cancer: early detection and treatment

• Screening: Light cancer with a low -dose CT is recommended for men with a high risk of lung cancer.
• Target therapy: Targeted therapy, aimed at specific molecular characteristics of lung cancer cells, is becoming more and more important.
• Immunotherapy: Immunotherapy shows promising results in the treatment of lung cancer.

XB cancer of the colon and rectum: screening and prevention

• Colonoscopy: Colonoscopy is a screening test that can be used to identify and remove polyps in the colon, which can prevent cancer of the colon and rectum.
• Surgical intervention: Surgical intervention is the main method of treating colon and rectum cancer.
• Chemotherapy: Chemotherapy can be used to destroy cancer cells after surgery or to treat metastatic cancer of the colon and rectum.

Xc bladder cancer: diagnosis and treatment

• Cystoscopy: Cystoscopy is a procedure in which a thin tube with a camera is introduced into the bladder to visualize the inner surface of the urine