Sexual health of men 2025: Recent achievements
I. Preventive medicine and early detection:
-
Genomatic testing and personalized approach:
- Identification of genetic risks: Genomal testing is becoming more accessible and allows you to identify a genetic predisposition to various diseases affecting the sexual health of men. This includes the risk of developing prostate cancer, erectile dysfunction (ED), hypogonadism and other conditions.
- Targeted prevention: Based on the results of genomic testing, individual prevention programs are developed, including changes in lifestyle, diet, physical exercises and, in some cases, pharmacological prevention.
- Early detection of diseases: Genomal testing can help in early detection of diseases, such as prostate cancer, allowing you to start treatment in the early stages, when it is most effective.
- Pharmacogenomy: Assessment of genetic variations affecting the metabolism of drugs allows optimizing the pharmacological treatment of diseases associated with sexual health, and minimize side effects. For example, in the treatment of ED FDE-5 inhibitors, genetic factors can be taken into account that affect the effectiveness and safety of these drugs.
- Ethical questions: The widespread use of genomic testing causes ethical issues related to the confidentiality of genetic information, the possibility of discrimination and the need for genetic counseling. It is necessary to develop clear ethical norms and rules governing the use of genomic information.
-
Biomarkers and non -invasive diagnostic methods:
- Liquid biopsy: A blood test or other biological fluids to detect biomarkers indicating the presence or progression of diseases affecting sexual health. For example, the definition of a prostatic specific antigen (PSA) in the blood is a screening method for identifying prostate cancer.
- Exosome: The study of exosos, microscopic vesicles secreted by cells to detect biomarkers of the prostate cancer and other diseases. Exosomas may contain DNA, RNA and proteins, which reflect the condition of the source cell.
- Metabolomics: Analysis of metabolites in biological fluids to detect metabolic changes associated with diseases affecting sexual health.
- Preview: Development of new visualization methods, such as multi-parametric magnetic resonance imaging (MPMT), for a more accurate diagnosis of prostate diseases and other pelvic organs. MPMRT allows you to visualize the tumors of the prostate gland and evaluate their aggressiveness.
- New biomarkers: The study of new biomarkers, such as PCA3 and TMPRSS2: ERG, to improve the diagnosis of prostate cancer and its differentiation from benign diseases.
- Artificial intelligence (AI): The use of AI for the analysis of medical images and data to improve the diagnosis and predicting diseases affecting sexual health. AI can help to identify prostate tumors on the MPMT and evaluate the risk of the progression of the disease.
-
Personalized screening programs:
- Age-dependent screening: Development of screening programs that take into account the age and risk factors for the development of diseases that affect sexual health.
- Risk-adapted screening: Adaptation of the frequency and intensity of screening, depending on the individual risk of the development of diseases. For example, men with a high risk of developing prostate cancer (family history, genetic predisposition) may need more frequent screening.
- Combined approaches: Using a combination of various screening methods (blood test, visualization, genetic testing) to increase the accuracy of diagnosis.
- Telemedicine: The use of telemedicine to conduct screening and advice on sexual health, especially in remote areas. Telemedicine allows patients to receive consultations of specialists and undergo a screening without the need to visit a medical institution.
- Self -study: Teaching men methods of self -examination of testicles for early detection of egg cancer.
-
Vaccination and immunotherapy:
- Vaccination against HPV: Vaccination against the human papilloma virus (HPV) for the prevention of cancer of the penis and other diseases associated with HPV.
- Prostate cancer immunotherapy: Development of new methods of immunotherapy for the treatment of prostate cancer. Immunotherapy stimulates the body’s immune system to combat cancer cells.
- Personalized immunotherapy: Development of personalized vaccines and other methods of immunotherapy adapted to the individual characteristics of the patient’s tumor.
- Combined therapy: Combining immunotherapy with other methods of treating prostate cancer, such as chemotherapy and radiation therapy.
II. Treatment of erectile dysfunction (ED):
-
New pharmacological drugs:
- New generation FDE-5 inhibitors: Development of FDE-5 inhibitors with improved pharmacokinetic properties, increased selectivity and fewer side effects.
- No-syntase activators: The development of drugs that activate NO-syntase, an enzyme involved in the synthesis of nitrogen oxide, which plays an important role in erection.
- Melanocortin receptor agonists: Development of drugs that activate melanocortin receptors that participate in the regulation of sexual excitement.
- Gene therapy: A study of the possibility of using genetic therapy for the treatment of ED.
-
Regenerative medicine:
- Stem cell injections: Injections of stem cells into the cavernous bodies of the penis to restore damaged tissues and improve erectile function.
- Injections of plasma platelets (PRP) enriched with platelets: PRP injections into the cavernous bodies of the penis to stimulate tissue regeneration and improve erectile function. PRP contains growth factors that contribute to the healing and regeneration of tissues.
- Clack engineering: Development of artificial fabrics to restore damaged cavernous bodies of penis.
-
Innovative surgical methods:
- Microsurgical reconstruction of cavernous arteries: The restoration of blood flow in the cavernous arteries using microsurgical methods for the treatment of ED caused by vascular disorders.
- Implantation of a new generation of penis: Development of more advanced penis prostheses with improved functionality and aesthetics.
- Robotized surgery: The use of robotic surgery to implant penis prostheses and other surgical interventions in ED.
-
Therapy using shock wave therapy (UVT):
- Low-intensity shock-wave therapy (NIVT): The use of NUVT to stimulate angiogenesis (the formation of new blood vessels) in the cavernous bodies of the penis and improve erectile function. NIUVT is a non -invasive and painless method of treatment Ed.
III. Treatment of premature ejaculation (PE):
-
New pharmacological drugs:
- Selective inhibitors of the reverse capture of serotonin (SIOS) of the prolonged action: Development of Sioles with a prolonged effect and smaller number of side effects for the treatment of PE.
- Antagonists 5-HT1A receptors: Development of drugs that block 5-HT1A receptors that participate in the regulation of ejaculation.
- Local anesthetics of a new generation: Development of local anesthetics with improved properties to reduce the sensitivity of the penis and extend the time before ejaculation.
-
Behavioral therapy and psychological support:
- “Start-stop” method: Teaching men “Start-stop” technique, which allows you to control ejaculation.
- Method “compression”: Teaching men “Compression” technique, which allows you to reduce sexual arousal and delay ejaculation.
- Cognitive-behavioral therapy (KPT): The use of KPT for the treatment of PE caused by psychological factors, such as anxiety and stress.
- Sexy therapy: Conducting sexual therapy to solve problems in relationships that PE can contribute to.
-
Innovative devices and methods:
- Devices for training the pelvic floor muscles: The use of devices for training the pelvic floor muscles that play a role in the control of ejaculation.
- Neuromodulation: A study of the possibility of using neuromodulation for the treatment of PE. Neuromodulation includes stimulation of nerves involved in the regulation of ejaculation using electrical or magnetic impulses.
IV. Treatment of hypogonadism (testosterone deficiency):
-
New forms of testosterone:
- Coral forms of testosterone: Development of oral forms of testosterone with improved bioavailability and lower risk of liver damage.
- Transdermal plasters and new generation gels: Development of transdermal plasters and gels with an improved release of testosterone and a more stable level of hormone in the blood.
- Injection forms of testosterone of prolonged action: Development of injection forms of testosterone with a prolonged effect that requires less frequent injection.
- Nazal forms of testosterone: Development of nasal forms of testosterone for quick and convenient administration of the drug.
-
Selective modulators of androgen receptors (SMAR):
- Development of new smarts: The development of new smarts that selectively stimulate androgen receptors in certain tissues, such as muscles and bones, and have a minimal effect on the prostate gland.
-
Stimulation of the production of your own testosterone:
- Clomiphene Citrate: The use of clomiphen citrate to stimulate the production of its own testosterone in men with secondary hypogonadism.
- Gonadotropin-releasing hormone (GNRG): The use of GNRG to stimulate the production of its own testosterone in men with hypogonadotropic hypogonadism.
-
Individual approach to treatment:
- Assessment of the causes of hypogonadism: A thorough assessment of the causes of hypogonadism for choosing the optimal treatment method.
- Testosterone level monitoring: Regular monitoring of the level of testosterone in the blood to adjust the dose of the drug.
- Accounting for related diseases: Accounting for concomitant diseases when choosing a method of treating hypogonadism.
V. Treatment of infertility in men:
-
Microsurgical methods:
- Microsurgical varicocelicectomy: Microsurgical treatment of varicocele (expansion of the veins of the seed) to improve sperm quality.
- Microsurgical vasoostomy and vasoepidyrostomy: Microsurgical restoration of the patency of the vasation of the ducts after vasectomy or other obstruction.
-
Auxiliary reproductive technologies (ART):
- Intracitoplasmic injection of a sperm (ICSI): The use of ICSI for fertilization of the egg with a sperm obtained from the testicle or appendage of the testicle.
- Extraction of sperm from the testis (TSE) and micro-TESE: The use of TSE and micro-TESE to obtain sperm from the testis in men with non-constructive azoospermia (lack of sperm in the ejaculate).
- Preimplantation genetic diagnostics (PGD): The use of PGD for the selection of embryos without genetic anomalies before implantation in the uterus.
-
Medication:
- Antioxidants: Using antioxidants to improve sperm quality.
- Clomiphene Citrate and Tamoxifen: The use of clomiphen citrate and tamoxifen to stimulate spermatogenesis.
- Follicle -stimulating hormone (FSG): The use of FSH to stimulate spermatogenesis in men with hypogonadotropic hypogonadism.
-
New methods of cryoconservation of sperm:
- Vitrification: The use of vitrification (ultra -fast freezing) for sperm cryoconservers, which allows you to maintain its quality better than with traditional freezing methods.
VI. Treatment of prostate diseases:
-
Prostate cancer:
- Robotized prostatectomy: The use of robotic surgery to remove the prostate gland with less invasiveness and more accurate preservation of the nerves responsible for the erectile function and maintaining urine.
- Focal therapy: The use of focal therapy (high -intensive focused ultrasound (HIFU), cryotherapy, photodynamic therapy) to destroy the tumor in the prostate gland, while maintaining a healthy tissue.
- Target therapy: The use of targeted therapy aimed at specific molecular targets in the cancer cells of the prostate gland.
- Radioactive implants (brachytherapy): The use of radioactive implants to irradiate the prostate tumor from the inside.
- Alpha therapy: The use of alpha-therapy (for example, radium-223) to treat the metastatic cancer of the prostate gland that affects the bone.
-
Benign prostate hyperplasia (DGPZH):
- Minimum invasive treatment methods: The use of the minimum invasive methods of treating DHCS, such as transuretral resection of the prostate gland (turp), laser enucleation of the prostate gland (Holep) and transurethral microwave thermal therapy (TUMT).
- Preparations to reduce the size of the prostate gland: The use of drugs, such as 5-alpha reductase inhibitors (finsteride, dutasteride), to reduce the size of the prostate gland.
- Alpha blockers: The use of alpha blockers to relax the muscles of the prostate gland and bladder and improve urination.
- Water vapor (rezum): The use of water vapor to reduce the size of the prostate gland.
- Embolization of the arteries of the prostate gland (EACG): The use of EACS to reduce the size of the prostate gland by blocking blood flow to the prostate gland.
-
Prostatitis:
- Individual approach to treatment: An individual approach to the treatment of prostatitis, taking into account the cause and type of prostatitis.
- Antibiotics: The use of antibiotics for the treatment of bacterial prostatitis.
- Alpha blockers: Using alpha blockers to alleviate the symptoms of prostatitis.
- Anti -inflammatory drugs: The use of anti -inflammatory drugs to reduce inflammation in the prostate gland.
- Physiotherapy: The use of physiotherapy to alleviate the symptoms of prostatitis.
VII. Treatment of penile diseases:
-
Peyroni disease:
- Collagena: Injections of collagenase in Payroni plaques to destroy collagen and straightening the penis.
- Vacuum devices: The use of vacuum devices to straighten the penis.
- Surgical treatment: Surgical treatment of Peyroni’s disease to straighten the penis.
-
PM cancer:
- Surgical treatment: Surgical treatment of penis cancer, including partial or complete amputation of the penis.
- Radiation therapy: Radiation therapy of penis cancer.
- Chemotherapy: Chemotherapy of penis cancer.
- Immunotherapy: Immunotherapy of penis cancer.
-
Balanitis and Balanoposthitis:
- Hygiene: Compliance with hygiene rules for the prevention and treatment of balanite and balanoposthitis.
- Antifungal drugs: The use of antifungal drugs for the treatment of fungal balanide and balanoposthitis.
- Antibacterial drugs: The use of antibacterial drugs for the treatment of bacterial balanite and balanoposthitis.
- Corticosteroids: The use of corticosteroids to reduce inflammation for balanite and balanopostitis.
- Circumcia (circumcision): Circumcia for the prevention of recurrent balanis and balanoposthitis.
VIII. Psychosexual health:
-
Integrative approach:
- Accounting for psychological and social factors: Accounting for psychological and social factors affecting the sexual health of men.
- Multidisciplinary team: The work of a multidisciplinary team, including urologists, andrologists, sexologists, psychologists and psychiatrists.
-
Sexy therapy:
- Treatment of sexual dysfunctions: Conducting sexual therapy for the treatment of sexual dysfunctions, such as a decrease in libido, anxiety associated with sexual activity, and problems in relationships.
- Work with sexual orientation and gender identity: Support and consultations for men experiencing difficulties with sexual orientation and gender identity.
-
Online consultations and telemedicine:
- Accessibility and confidentiality: Providing online consultations and telemedicines to improve access to specialized assistance and provide confidentiality.
-
Education and Education:
- Improving awareness of sexual health: Improving awareness of sexual health of men through educational programs and campaigns.
- Stegma removal: Removing stigma related to sexual health problems.
- Prevention of sexually transmissive infections (styles): Prevention of style through educational programs and promoting safe sex.
IX. A healthy lifestyle and its effect on sexual health:
-
Proper nutrition:
- Balanced diet: Maintaining a balanced diet rich in fruits, vegetables, whole grains and low -fat protein.
- Limiting the consumption of fats, sugar and processed products: Limiting the consumption of fats, sugar and processed products that can negatively affect sexual health.
- Sufficient consumption of vitamins and minerals: Providing sufficient consumption of vitamins and minerals, such as vitamin D, zinc and selenium, which play an important role in sexual health.
-
Physical activity:
- Regular physical exercises: Regular physical exercises to maintain healthy weight, improve blood circulation and reduce the risk of developing diseases affecting sexual health.
- Exercises for the muscles of the pelvic floor: Performing exercises for the pelvic floor muscles to improve ejaculation control and maintain erectile function.
-
Weight control:
- Maintaining a healthy weight: Maintaining a healthy weight to reduce the risk of developing diseases, such as diabetes, cardiovascular diseases and ED.
-
Refusal of smoking and abuse of alcohol:
- Refusal of smoking: Refusal of smoking, which negatively affects blood circulation and can lead to ED.
- Moderate alcohol consumption: Moderate alcohol consumption, since alcohol abuse can negatively affect sexual health.
-
Stress management:
- Relaxation methods: The use of relaxation methods, such as meditation, yoga and deep breathing, to control stress.
- Sufficient sleep: Ensuring sufficient sleep, since a lack of sleep can negatively affect sexual health.
X. Technologies and innovations in the field of sexual health:
-
Telemedicine and remote monitoring:
- Consultations with doctors online: The opportunity to consult online sexual health.
- Remote monitoring: Remote monitoring of patients of patients using wearable devices and mobile applications.
-
Sexual health applications:
- Tracking sexual activity: Applications for tracking sexual activity and symptoms of sexual dysfunctions.
- Training programs and resources: Applications with training programs and resources on sexual health issues.
-
Virtual reality (VR):
- Sexy therapy using VR: The use of VR for sexual therapy and treatment of sexual dysfunctions.
- Sexual health training using VR: The use of VR to teach sexual health and prevention prevention.
-
Artificial intelligence (AI):
- Diagnosis and treatment of diseases: The use of AI for the diagnosis and treatment of diseases affecting sexual health.
- Personalized recommendations: The use of AI to provide personalized recommendations for maintaining sexual health.
-
3D printing:
- Making penis prostheses: The use of 3D printing for the manufacture of penis prostheses and other medical devices.
XI. Ethics and legal aspects:
-
Confidentiality:
- Protection of personal information: Ensuring the protection of personal information of patients who seek help from sexual health.
- Compliance with the rules of confidentiality: Compliance with the rules of confidentiality by doctors and medical workers.
-
Informed consent:
- Obtaining informed consent to treatment: Obtaining informed consent to treatment in patients who seek help from sexual health.
- Providing complete information about the risks and advantages of treatment: Providing complete information about the risks and advantages of treatment.
-
Accessibility:
- Ensuring access to medical care: Ensuring access to medical care on sexual health for all men, regardless of age, race, ethnicity, sexual orientation and socio-economic status.
- Elimination of barriers: Elimination of barriers that impede access to medical care on sexual health, such as Stigma, lack of information and geographical remoteness.
-
Legal norms:
- Compliance with legal norms: Compliance with legal norms governing sexual health, such as the age of consent and protection against sexual violence.
XII. Trends and forecasts:
-
References growth:
- Improving awareness of sexual health: An increase in awareness of sexual health of men and a decrease in stigma related to sexual health problems is expected.
-
Personalized medicine:
- The development of personalized medicine: The development of personalized medicine in sexual health is expected, which will develop individual treatment and prevention plans based on genetic and other factors.
-
Technological progress:
- Implementation of new technologies: The introduction of new technologies in sexual health, such as telemedicine, VR and AI, is expected.
-
Integrative approach:
- Integration of psychological and social assistance: The integration of psychological and social assistance into the healthcare system is expected to ensure a comprehensive approach to the treatment of sexual health problems.
-
Preventive medicine:
- The emphasis on preventive medicine: An emphasis on preventive medicine and early detection of diseases affecting sexual health is expected.